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For your skin care products to be effective, they need to be able to reach each layer and perform different biological work. Z. Bigatti uses a process called cold-extraction and nano technology to isolate active ingredients that can penetrate and repair the middle layer, while protecting the third, youthful layer. What are peptides? Peptides are a growing trend in anti-aging skin care. They help you produce collagen and elastin that help plump the skin and give it elasticity. Z. Bigatti products contain peptides, including Acetyl Hexapeptide-3 that helps smooth out deep wrinkles.